the effect of eight weeks moderate intensity aerobic training on obestatin and ghrelin of obese male rats

aim of present research was to review the probability changes in ghrelin and obestatin hormones following eight weeks aerobic training with moderate intensity in sprague–dawley male rats. for this purpose randomly selected 47 two month age rats from animal lab. all rats made fat by stimulate the appetite with lettuce and vegetables and reached from mean weight 240±15 to 320±20 kg and after that randomly divided to two groups (control=23 and training=24). the training program of training group included eight weeks running on rodent specific treadmill; in parallel control group in this period of the time had no training. at the end for review the research variables, blood samples collected directly from the heart. for statistic analysis of data used independent t test. findings showed that eight weeks moderate intensity aerobic training made significant reduction in obestatin (p=000); also this training had no significant effect on ghrelin (p=0/99). regard to findings of research it conclude that eight weeks moderate intensity aerobic training can induces reduction in obestatin nevertheless does not affect ghrelin.